Renowned for its pivotal role in research, the roundworm Caenorhabditis elegans, or “the worm,” offers insights into biology and genetics. Recently, Princeton researchers discovered that after ingesting harmful bacteria, C. elegans passed on avoidance behavior to offspring for up to four generations. This transgenerational learning, mediated by small RNA molecules, raises intriguing parallels with human biology. RNA interference mechanisms, crucially identified in C. elegans, facilitate this phenomenon. Such discoveries underscore the worm’s profound impact on scientific understanding and hint at broader implications for human health and behavior.